G8898
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G8898
Sigma
Glycine
for electrophoresis, ≥99%
| Synonym: | Aminoacetic acid, Aminoethanoic acid, Glycocoll |
| CAS Number: | 56-40-6 |
| Linear Formula: | NH2CH2COOH |
| Molecular Weight: | 75.07 |
| Beilstein Registry Number: | 635782 |
| EC Number: | 200-272-2 |
| MDL number: | MFCD00008131 |
| PubChem Substance ID: | 24895355 |
Description
| Analysis Note | Tested for use in electrode buffers for PAGE and in transfer buffers for Western blots. |
| Application | Glycine is a component of Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis1. Glycine is also a component of Towbin′s transfer buffer for Western blots2. |
| Biochem/physiol Actions | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
Properties
| grade | for electrophoresis |
| assay | ≥99% |
| total impurities | ≤0.01% Insoluble matter |
| pKa (25 °C) | 2.35 |
| mp | 240 °C (dec.)(lit.) |
| anion traces | chloride (Cl-): ≤70 ppm |
| cation traces | heavy metals (as Pb): ≤20 ppm |
| abs. | A |
| Gene Information | rat ... Grin2a(24409) |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| Safety Statements | 22-24/25 |
| WGK Germany | 1 |
| RTECS | MB7600000 |
References
| Cited Reference | 1. Hames, B.D. and Rickwood, D. Gel Electrophoresis of Proteins: A Practical Approach 2nd ed., New York, NY , (1990), 32-35 |
| 2. Towbin, H., et al., Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U. S. A. 76, 4350, (1979) Abstract | |
| reference | Laemmli, U.K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685, (1970) Abstract |
| Merck | Merck 13,4504 |
| Beilstein | Beil. 4,IV,2349 |
| Fieser | Fieser 1,412 |
| Corp MSDS 1 (1), 1786:D / FT-IR 1 (1), 563:A / FT-IR 2 (1), 898:A / FT-NMR 1 (1), 867:A / Fenaroli, 307 / IR-Spectra (2), 302:A / IR-Spectra (3), 338:A / NMR-Reference 2 (1), 481:A / RegBook 1 (1), 645:A / Sax 6, 1481 / Sigma FT-IR 1 (1), 176:B / Structure Index 1, 94:A:1 |
